Nailfold capillaroscopy

Specific changes on nailfold capillaroscopy are found in systemic sclerosis, dermatomyositis and anti-U1-RNP positive mixed connective tissue disease. Nailfold capillaroscopy is used for the early diagnosis and recognition of these connective tissue diseases. Nailfold capillaroscopy can also be used to evaluate the risk for digital ulcers in patients with systemic sclerosis.

Using modern nail fold capillaroscopy equipment, different features of the nailfold capillaries are assessed and quantified. Typical changes include capillary dilatation and megacapillaries, rarefication, microhemorrhages, and different forms of disturbed angiogenesis.

Patients, for whom no additional assessments are required, can be specifically sent for nailfold capillaroscopy to our outpatient clinic. ​

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Capillaroscopy from a patient with SSc showing megacapillaries (arrows) and a microhemorrhage (dark
blue
arrow)
Normal capillaroscopy from a healthy person.