The Clinic for Rheumatology is actively pursuing the search for molecular pathways operating in the pathogenesis of rheumatic diseases (Center for Experimental Rheumatology) and evaluating novel therapeutic strategies for treatment (Clinical Trials).
The focus of basic research centers around the epigenetic dysregulation of gene expression (functional genomics) in rheumatic diseases, such as rheumatoid arthritis, ankylosing spondylitis and systemic sclerosis (Scleroderma). Thereby novel targets are explored with the strategy to develop better specific therapies with less side effects.
The clinical research focuses on the analysis of quality standards in clinical care, biomarkers for disease activity and the development of novel therapeutic strategies for the treatment of rheumatic diseases. Thereby, promising drugs in development by the pharmaceutical industry are critically evaluated by participation in international trial consortia.
More detailed information on the specific research projects carried out at the Clinic for Rheumatology can be found at the Forschungsdatenbank der Universität Zürich