Complex regional pain syndrome
Complex regional pain syndrome (CRPS) is a condition of extreme pain affecting a part of the body with clinical features including chronic inflammation, sensory and motor dysfunctions and changes to skin and bones. Symptoms usually appear after trauma or surgery. (Read more...
Current in vitro models for skin diseases are based on cell monolayers, not considering the complex interaction within the 3-dimensional architecture of organs and the interactions of cells and the environment. Consequently, we observe a rather poor predictable power of pre-clinical cell-based drug screening assays.