This study, financed by the Swiss National Science Foundation, aims to examine direct relatives of patients with RA before the outbreak of the disease and to monitor them on a longer term. Although 1% of the population suffers rheumatoid arthritis, their relatives are affected 3-6 times more.
link to www.arthritis-checkup.ch
Published studies (selection)
The prevalence of anticitrullinated protein antibodies increases with age in healthy individuals at risk for rheumatoid arthritis. Alpizar-Rodriguez D, Brulhart L, Mueller RB, Möller B, Dudler J, Ciurea A, Walker UA, Von Mühlenen I, Kyburz D, Zufferey P, Mahler M, Bas S, Gascon D, Lamacchia C, Roux-Lombard P, Lauper K, Nissen MJ, Courvoisier DS, Gabay C, Finckh A. Clin Rheumatol. ;36:677-82, 2017.
Female hormonal factors and the development of anti-citrullinated protein antibodies in women at risk of rheumatoid arthritis. Alpizar-Rodriguez D, Mueller RB, Möller B, Dudler J, Ciurea A, Zufferey P, Kyburz D, Walker UA, von Mühlenen I, Roux-Lombard P, Mahler M, Lamacchia C, Courvoisier DS, Gabay C, Finckh A. Rheumatology (Oxford). 56:1579-85, 2017.